2021

2021 Issue 12

One new cochrane review  is published in Issue 12 of the   Cochrane Database of Systematic Reviews.

New Cochrane Review

Lutje V, Seixas J, Kennedy A. Chemotherapy for second‐stage Human African trypanosomiasis. Cochrane Database of Systematic Reviews 2013, Issue 6. Art. No.: CD006201. DOI: 10.1002/14651858.CD006201.pub3

2021 Issue 11

One Cochrane review update is published in Issue 11 of the   Cochrane Database of Systematic Reviews.

Updated Review

2021 Issue 10

No new or updated publications to report in Issue 10 2021

2021 Issue 9

Two new Cochrane protocols and one updated Cochrane review are published  in Issue 9, 2021 of the Cochrane Database of Systematic Reviews.

Updated Review

  • Shah MP, Hwang J, Choi L, Lindblade KA, Kachur SP, Desai M. Mass drug administration for malaria. Cochrane Database of Systematic Reviews 2021, Issue 9. Art. No.: CD008846. DOI: 10.1002/14651858.CD008846.pub3

New Protocols

2021 Issue 8

Two new Cochrane reviews are published in Issue 8, 2021 of the Cochrane Database of Systematic Reviews. 

New Cochrane Reviews

Ochodo  EA, Guleid  F, Deeks  JJ, Mallett  S. Point‐of‐care tests detecting HIV nucleic acids for diagnosis of HIV‐1 or HIV‐2 infection in infants and children aged 18 months or less. Cochrane Database of Systematic Reviews 2021, Issue 8. Art. No.: CD013207. DOI: 10.1002/14651858.CD013207.pub2.


Nathavitharana RR, Lederer P, Chaplin M, Bjerrum S, Steingart KR, Shah M. Impact of diagnostic strategies for tuberculosis using lateral flow urine lipoarabinomannan assay in people living with HIV. Cochrane Database of Systematic Reviews 2021, Issue 8. Art. No.: CD014641. DOI: 10.1002/14651858.CD014641.

2021 Issue 7

One new Cochrane review is published in Issue 7, 2021 of the Cochrane Database of Systematic Reviews. 

New Cochrane Review

Popp M, Stegemann M, Metzendorf M-I, Gould S, Kranke P, Meybohm P, Skoetz N, Weibel S. Ivermectin for preventing and treating COVID‐19. Cochrane Database of Systematic Reviews 2021, Issue 7. Art. No: CD015017. DOI: 10.1002/14651858.CD015017.pub2

2021 Issue 6

Two Cochrane protocols, two new Cochrane reviews, and one Cochrane review update are published  in Issue 6, 2021 of the Cochrane Database of Systematic Reviews.

New Protocols

Leeflang MMG, Bell K, Deeks JJ, Dinnes J, Doust J, Korevaar DA, Lord SJ, Spijker R. Electronic and animal noses for detecting SARS‐CoV‐2 infection. Cochrane Database of Systematic Reviews 2021, Issue 6. Art. No.: CD015013. DOI: 10.1002/14651858.CD015013 

Pillay S, Davies GR, Chaplin M, De Vos M, Schumacher SG, Warren R, Steingart KR, Theron G. Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin. Cochrane Database of Systematic Reviews 2021, Issue 6. Art. No.: CD014841. DOI: 10.1002/14651858.CD014841

 New Cochrane Reviews

Vonasek B, Ness T, Takwoingi Y, Kay AW, van Wyk SS, Ouellette L, Marais BJ, Steingart KR, Mandalakas AM. Screening tests for active pulmonary tuberculosis in children. Cochrane Database of Systematic Reviews 2021, Issue 6. Art. No.: CD013693. DOI: 10.1002/14651858.CD013693.pub2

de Souza DK, Thomas R, Bradley J, Leyrat C, Boakye DA, Okebe J. Ivermectin treatment in humans for reducing malaria transmission. Cochrane Database of Systematic Reviews 2021, Issue 6. Art. No.: CD013117. DOI: 10.1002/14651858.CD013117.pub2

 Updated Cochrane Review 

Monk EJM, Abba K, Ranganathan LN. Anthelmintics for people with neurocysticercosis. Cochrane Database of Systematic Reviews 2021, Issue 6. Art. No.: CD000215. DOI: 10.1002/14651858.CD000215.pub5

Issue 5

Two new Cochrane reviews and one Cochrane review update are published in Issue 5, 2021 of the Cochrane Database of Systematic Reviews 

 New Cochrane Reviews

Haraka F, Kakolwa M, Schumacher SG, Nathavitharana RR, Denkinger CM, Gagneux S, Reither K, Ross A. Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis. Cochrane Database of Systematic Reviews 2021, Issue 5. Art. No.: CD012972. DOI: 10.1002/14651858.CD012972.pub2.


Anton-Vazquez V, Hine P, Krishna S, Chaplin M, Planche T. Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection. Cochrane Database of Systematic Reviews 2021, Issue 5. Art. No.: CD013235. DOI: 10.1002/14651858.CD013235.pub2.

 Updated Cochrane Review 

Gleave K, Lissenden N, Chaplin M, Choi L, Ranson H. Piperonyl butoxide (PBO) combined with pyrethroids in insecticide‐treated nets to prevent malaria in Africa. Cochrane Database of Systematic Reviews 2021, Issue 5. Art. No.: CD012776. DOI: 10.1002/14651858.CD012776.pub3.

2021 Issue 4

No new or updated publications to report in Issue 4 2021

2021 Issue 3

One new Cochrane protocol, one new Cochrane review, and two updated COVID-19 Cochrane reviews are published in Issue 3, 2021 of the Cochrane Database of Systematic Reviews.

New Protocol

Medley  N, Taylor  M, Wyk  SS, Oliver  S. Community views on active case finding for tuberculosis in low- and middle-income countries: a qualitative evidence synthesis. Cochrane Database of Systematic Reviews 2021, Issue 3. Art. No.: CD014756. DOI: 10.1002/14651858.CD014756.

 New Cochrane Review

Shapiro  AE, Ross  JM, Yao  M, Schiller  I, Kohli  M, Dendukuri  N, Steingart  KR, Horne  DJ. Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults, irrespective of signs or symptoms.  Cochrane Database of Systematic Reviews 2021, Issue 3. Art. No.: CD013694. DOI: 10.1002/14651858.CD013694.pub2.

 Two updated COVID 19 DTA Reviews

Dinnes  J, Deeks  JJ, Berhane  S, Taylor  M, Adriano  A, Davenport  C, Dittrich  S, Emperador  D, Takwoingi  Y, Cunningham  J, Beese  S, Domen  J, Dretzke  J, Ferrante di Ruffano  L, Harris  IM, Price  MJ, Taylor-Phillips  S, Hooft  L, Leeflang  MMG, McInnes  MDF, Spijker  R, Van den Bruel  A. Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection. Cochrane Database of Systematic Reviews 2021, Issue 3. Art. No.: CD013705. DOI: 10.1002/14651858.CD013705.pub2

Islam  N, Ebrahimzadeh  S, Salameh  J-P, Kazi  S, Fabiano  N, Treanor  L, Absi  M, Hallgrimson  Z, Leeflang  MMG, Hooft  L, Pol  CB, Prager  R, Hare  SS, Dennie  C, Spijker  R, Deeks  JJ, Dinnes  J, Jenniskens  K, Korevaar  DA, Cohen  JF, Van den Bruel  A, Takwoingi  Y, de Wijgert  J, Damen  JAAG, Wang  J, McInnes  MDF. Thoracic imaging tests for the diagnosis of COVID‐19. Cochrane Database of Systematic Reviews 2021, Issue 3. Art. No.: CD013639. DOI: 10.1002/14651858.CD013639.pub4.

2021 Issue 2

One new COVID-19 review, one updated COVID-19 review, and one updated Cochrane review  are published  in Issue 2, 2021 of the Cochrane Database of Systematic Reviews.

New COVID 19 Review

Singh  B, Ryan  H, Kredo  T, Chaplin  M, Fletcher  T. Chloroquine or hydroxychloroquine for prevention and treatment of COVID‐19. Cochrane Database of Systematic Reviews 2021, Issue 2. Art. No.: CD013587. DOI: 10.1002/14651858.CD013587.pub2
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 Updated COVID 19 Review 

Struyf  T, Deeks  JJ, Dinnes  J, Takwoingi  Y, Davenport  C, Leeflang  MMG, Spijker  R, Hooft  L, Emperador  D, Domen  J, Horn  SR A, Van den Bruel  A. Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19. Cochrane Database of Systematic Reviews 2021, Issue 2. Art. No.: CD013665. DOI: 10.1002/14651858.CD013665.pub2. 
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 Updated Cochrane Review 

Zifodya  JS, Kreniske  JS, Schiller  I, Kohli  M, Dendukuri  N, Schumacher  SG, Ochodo  EA, Haraka  F, Zwerling  AA, Pai  M, Steingart  KR, Horne  DJ. Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis. Cochrane Database of Systematic Reviews 2021, Issue 2. Art. No.: CD009593. DOI: 10.1002/14651858.CD009593.pub5. 

2021 Issue 1

Two updated Cochrane reviews and one new protocol are published  in Issue 1, 2021 of the Cochrane Database of Systematic Reviews.

New Protocol

Weeratunga  P, Bancone  G, Ochodo  EA, Pant  S, Thapa  J, Chaplin  M. Glucose‐6‐phosphate dehydrogenase deficiency near‐patient tests for tafenoquine or primaquine use with Plasmodium vivax malaria. Cochrane Database of Systematic Reviews 2021, Issue 1. Art. No.: CD013861. DOI: 10.1002/14651858.CD013861

Updated Reviews

Blanshard  A, Hine  P. Atovaquone‐proguanil for treating uncomplicated Plasmodium falciparum malaria. Cochrane Database of Systematic Reviews 2021, Issue 1. Art. No.: CD004529. DOI: 10.1002/14651858.CD004529.pub3 

Kohli  M, Schiller  I, Dendukuri  N, Yao  M, Dheda  K, Denkinger  CM, Schumacher  SG, Steingart  KR. Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults. Cochrane Database of Systematic Reviews 2021, Issue 1. Art. No.: CD012768. DOI: 10.1002/14651858.CD012768.pub3