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During June 2022, the CIDG published one new review, and two updated reviews in Issue 6, 2022 of the Cochrane Database of Systematic Reviews.New Review Garn JV, Wilkers JL, Meehan AA, Pfadenhauer LM, Burns J, Imtiaz R, Freeman MC. Interventions to improve water, sanitation, and hygiene for preventing soil-transmitted helminth infection...
June 30 2022
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What is the aim of this review?This review summarizes randomized controlled trials (RCTs) (studies where participants are randomly assigned to one of two or more treatment groups) and non‐randomized trials (non‐RCTs) evaluating the effect of water, sanitation, and hygiene interventions on preventing soil‐transmitted helminth infections. Soil‐...
June 22 2022
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What is the aim of this review?The aim of this Cochrane Review was to find out if the antimalarial drug pyronaridine‐artesunate is effective and safe in treating uncomplicated cases of an important type of malaria (Plasmodium falciparum). We collected and analysed all relevant studies to answer this question and found 10 studies.Key...
June 22 2022
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There remains no evidence to support the use of ivermectin for treating or preventing COVID-19 infection, state the authors of an updated Cochrane Review, which now contains 11 trials across 3409 people. The authors note that evidence is limited, and evaluation of ivermectin is continuing in ongoing studies. Ivermectin, a drug used to...
June 22 2022
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In this instalment of the CIDG 'Meet the Editor' series, we talk with Dr Joseph Pryce from the UK. Before becoming a CIDG Editor, Joe worked as a Research Assistant at the CIDG editorial base in Liverpool. In that role he produced a series of systematic reviews that assessed the impact of vector-control interventions on malaria...
May 26 2022
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How accurate are symptoms and medical examination to diagnose COVID‐19?Key messages‐ The results suggest that a single symptom included in this review cannot accurately diagnose COVID‐19.‐ Loss of sense of taste or smell could be a 'red flag' for the presence of COVID‐19. Cough or fever might be useful to identify people who might have COVID‐19....
May 26 2022
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Why is improving the diagnosis of tuberculosis drug resistance important?Tuberculosis tests, like Xpert MTB/RIF, Xpert MTB/RIF Ultra, and Truenat, only diagnose rifampicin resistance, but do not provide information about resistance to other drugs used to treat tuberculosis. This information is needed to allow for effective treatment to be started...
May 24 2022
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How accurate is chest imaging for diagnosing COVID‐19?Why is this question important?People with suspected COVID‐19 need to know quickly whether they are infected, so they can receive appropriate treatment, self‐isolate, and inform close contacts.Currently, a formal diagnosis of COVID‐19 requires a laboratory test (RT‐PCR) of nose and throat...
May 17 2022
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During April 2022, the CIDG published one new protocol and one new review in Issue 4, 2022 of the Cochrane Database of Systematic Reviews.New Protocol Reis S, Popp M, Kuehn R, Metzendorf M-I, Gagyor I, Kranke P, Meybohm P, Skoetz N, Weibel S. Nirmatrelvir combined with ritonavir for preventing and treating COVID‐19. Cochrane Database of...
April 28 2022
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A potential game-changer in the tuberculosis epidemic was how the tuberculosis community viewed rapid molecular tests for tuberculosis and tuberculosis drug resistance. This was 12 years ago, with the launch of Xpert MTB/RIF, which gives results in less than two hours, simultaneously diagnosing tuberculosis and testing if the bacteria have...
April 26 2022
During June 2022, the CIDG published one new review, and two updated reviews in Issue 6, 2022 of the Cochrane Database of Systematic Reviews.New Review Garn JV, Wilkers JL, Meehan AA, Pfadenhauer LM, Burns J, Imtiaz R, Freeman MC. Interventions to improve water, sanitation, and hygiene for preventing soil-transmitted helminth infection...June 30 2022
What is the aim of this review?This review summarizes randomized controlled trials (RCTs) (studies where participants are randomly assigned to one of two or more treatment groups) and non‐randomized trials (non‐RCTs) evaluating the effect of water, sanitation, and hygiene interventions on preventing soil‐transmitted helminth infections. Soil‐...June 22 2022
What is the aim of this review?The aim of this Cochrane Review was to find out if the antimalarial drug pyronaridine‐artesunate is effective and safe in treating uncomplicated cases of an important type of malaria (Plasmodium falciparum). We collected and analysed all relevant studies to answer this question and found 10 studies.Key...June 22 2022
There remains no evidence to support the use of ivermectin for treating or preventing COVID-19 infection, state the authors of an updated Cochrane Review, which now contains 11 trials across 3409 people. The authors note that evidence is limited, and evaluation of ivermectin is continuing in ongoing studies. Ivermectin, a drug used to...June 22 2022
In this instalment of the CIDG 'Meet the Editor' series, we talk with Dr Joseph Pryce from the UK. Before becoming a CIDG Editor, Joe worked as a Research Assistant at the CIDG editorial base in Liverpool. In that role he produced a series of systematic reviews that assessed the impact of vector-control interventions on malaria...May 26 2022
How accurate are symptoms and medical examination to diagnose COVID‐19?Key messages‐ The results suggest that a single symptom included in this review cannot accurately diagnose COVID‐19.‐ Loss of sense of taste or smell could be a 'red flag' for the presence of COVID‐19. Cough or fever might be useful to identify people who might have COVID‐19....May 26 2022
Why is improving the diagnosis of tuberculosis drug resistance important?Tuberculosis tests, like Xpert MTB/RIF, Xpert MTB/RIF Ultra, and Truenat, only diagnose rifampicin resistance, but do not provide information about resistance to other drugs used to treat tuberculosis. This information is needed to allow for effective treatment to be started...May 24 2022
How accurate is chest imaging for diagnosing COVID‐19?Why is this question important?People with suspected COVID‐19 need to know quickly whether they are infected, so they can receive appropriate treatment, self‐isolate, and inform close contacts.Currently, a formal diagnosis of COVID‐19 requires a laboratory test (RT‐PCR) of nose and throat...May 17 2022