Vaccines for preventing rotavirus diarrhoea: vaccines in use 

Rotavirus infection is a common cause of diarrhea and a variety of vaccines are used to try to prevent it. The evidence for these is examined in the fourth update of a Cochrane Review, published in March 2019 . Hanna Bergman one of the authors based in the Cochrane Response team in London UK tells us  about the problem and the latest findings.

Xpert® MTB/RIF  assay for extrapulmonary tuberculosis and rifampicin resistance 

Most Cochrane Reviews look at the effects of interventions on health, but a growing number are providing evidence on the accuracy of different ways of diagnosing a disease. These were added to in August 2018 by a new review on a test used in the management of tuberculosis. The review's first author, Mikashmi Kohli from McGill University in Montreal Canada, sets the scene and tells us what they found in this podcast.

Kohli M, Schiller I, Dendukuri N, Dheda k, Denkinger CM, Schumacher SG, Steingart KR

Podcast published October 2018

The accuracy of rapid diagnostic tests  for detecting typhoid and paratyphoid (enteric) fever

Point-of-care rapid diagnostic tests which use a small amount of blood are available for infectious diseases such as malaria and HIV, and make an important contribution to patient management. Cochrane reviews of the accuracy of such tests have influenced WHO policy and, in May 2017, they were added to with a new Cochrane Diagnostic Test Accuracy review of rapid tests for typhoid and paratyphoid fevers. Lalith Wijedoru from the Alder Hey Children's Hospital in Liverpool in UK tells us more in this podcast.

Wijedoru L, Mallett S, Parry CM

Podcast published October 2017

Also recorded in Croatian 

Podcast published May 2018

School-based interventions for preventing HIV, sexually transmitted infections,
and pregnancy in adolescents

Mason-Jones AJ, Sinclair D, Mathews C, Kagee A, Hillman A, Lombard C

Podcast published March 2017


BMJ talk medicine: Stopping the overtreatment of malaria

Rapid diagnostic tests have the potential to reduce the overtreatment of malaria by 95%, but time and extensive logistical, behavioural, and technical interventions may be required to achieve this. Eleanor Ochodo from the Centre for Evidence-based Health Care at Stellenbosch University discusses.

Read the full BMJ article: Ochodo E, Garner P, Sinclair D (2016) Achieving universal testing for malaria BMJ 352:i107

Published 04 February 2016

Directly observed therapy for treating tuberculosis

Jamlick Karumbi, Paul Garner 

Published 23 July 2015

Intermittent preventive antimalarial treatment for children with anaemia

Anke Rohwer, based at the Centre for Evidence-based Health Care at Stellenbosch University in South Africa, describes the rationale and findings in this Evidence Podcast.

Published 13 January 2015


LSTM Podcast March 2014

Professor Paul Garner discusses his work as CIDG Coordinating Editor.


Drugs for treating urinary schistosomiasis 

Kramer CV, Zhang F, Sinclair D, Olliaro P

Published 6 August 2014


Xpert® MTB/RIF test for diagnosing pulmonary tuberculosis and rifampicin resistance in adults

Steingart KR, Schiller I, Horne DJ, Pai M, Boehme CC, Dendukuri N

Published 21 January 2014


Deworming drugs for treating soil-transmitted intestinal worms in children: effects on nutrition and school performance 

Taylor-Robinson DC, Maayan N, Soares-Weiser K, Donegan S, Garner P

Published 14 November 2012


Vaccines for preventing rotavirus diarrhoea: vaccines in use 

Soares-Weiser K, MacLehose H, Bergman H, Ben-Aharon I, Nagpal S, Goldberg E, Pitan F, Cunliffe N

Published 14 November 2012


Strategies to encourage hand washing can reduce the incidence of diarrhoea by about one third 

Ejemot-Nwadiaro RI, Ehiri JE, Meremikwu MM, Critchley JA

Published 15 February 2012


Rapid diagnostic tests for diagnosing malaria 

Abba K, Deeks JJ, Olliaro PL, Naing C-M, Jackson SM, Takwoingi Y, Donegan S, Garner P

Published 18 January 2012


Probiotics for treating acute infectious diarrhoea

Allen SJ, Martinez EG, Gregorio GV, Dans LF

Published 8 December 2010


Drugs for preventing malaria in travellers 

Jacquerioz FA, Croft AM

Published 7 July 2010