2020 Issue 6

Three new protocols and two new reviews are available in Issue 6 of the Cochrane Database of Systematic Reviews

New COVID-19 Reviews

Deeks JJ, Dinnes J, Takwoingi Y, Davenport C, Spijker R, Taylor-Phillips S, Adriano A, Beese S, Dretzke J, Ferrante di Ruffano L, Harris IM, Price MJ, Dittrich S, Emperador D, Hooft L, Leeflang MMG, Van den Bruel A. Antibody tests for identification of current and past infection with SARSCoV2. Cochrane Database of Systematic Reviews 2020, Issue 6. Art. No.: CD013652. DOI: 10.1002/14651858.CD013652.

New Reviews

Jullien S, Dissanayake HA, Chaplin M. Rapid diagnostic tests for plague. Cochrane Database of Systematic Reviews 2019, Issue 10. Art. No.: CD013459. DOI: 10.1002/14651858.CD013459.pub2.

New COVID-19 Protocols

McInnes MDF, Leeflang MMG, Salameh J-P, McGrath TA, Pol CB, Frank RA, Prager R, Hare SS, Dennie C, Spijker R, Deeks JJ, Dinnes J, Jenniskens K, Korevaar DA, Cohen JF, Van den Bruel A, Takwoingi Y, de Wijgert J, Damen JAAG, Hooft L. Imaging tests for the diagnosis of COVID19. Cochrane Database of Systematic Reviews 2020, Issue 6. Art. No.: CD013639. DOI: 10.1002/14651858.CD013639.

New Protocols

Florez ID, Sierra J, Pérez-Gaxiola G. Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children. Cochrane Database of Systematic Reviews 2020, Issue 6. Art. No.: CD013640. DOI: 10.1002/14651858.CD013640.

Taylor M, Oliver S, Garner P. Mass drug administration for filariasis: community views and programme design influences a qualitative evidence synthesis. Cochrane Database of Systematic Reviews 2020, Issue 6. Art. No.: CD013638. DOI: 10.1002/14651858.CD013638.

2020 Issue 5

No publications produced for Issue 5

2020  Issue  4 

Four new reviews and two new protocols are available in Issue 4 of the Cochrane Database of Systematic Reviews 

New COVID-19 Reviews

Nussbaumer‐Streit  B, Mayr  V, Dobrescu  AI, Chapman  A, Persad  E, Klerings  I, Wagner  G, Siebert  U, Christof  C, Zachariah  C, Gartlehner  G. Quarantine alone or in combination with other public health measures to control COVID‐19: a rapid review. Cochrane Database of Systematic Reviews 2020, Issue 4. Art. No.: CD013574. DOI: 10.1002/14651858.CD013574

This review is part of Cochrane's work on Rapid Reviews in response to COVID-19. The review was   commissioned by WHO and prepared by a Cochrane Austria team led by Barbara Nussbaumer‐Streit. The review’s aim is to assess the effects of quarantine (alone or in combination with other measures) of individuals who had contact with confirmed cases of COVID‐19, who travelled from countries with a declared outbreak, or who live in regions with high transmission of the disease. It includes cohort studies, case‐control‐studies, case series, time series, interrupted time series, and mathematical modelling studies that assessed the effect of any type of quarantine to control COVID‐19, as well as studies on SARS (severe acute respiratory syndrome) and MERS (Middle East respiratory syndrome). The authors included 29 studies; 10 modelling studies on COVID‐19, four observational studies and 15 modelling studies on SARS and MERS. Because of the diverse methods of measurement and analysis it was not possible to conduct a meta‐analysis and the authors conducted a narrative synthesis. Modeling studies consistently reported a benefit of the simulated quarantine measures, for example, quarantine of people exposed to confirmed or suspected cases averted 44% to 81% incident cases and 31% to 63% of deaths compared to no measures. When the models combined quarantine with other prevention and control measures, including school closures, travel restrictions and social distancing, the models demonstrated a larger effect on the reduction of new cases, transmissions and deaths than individual measures alone. The authors conclude that quarantine is important in reducing incidence and mortality during the COVID‐19 pandemic, and it is important to constantly monitor the outbreak situation and the impact of the measures implemented. A summary of this review is also available as a podcast and as Cochrane Clinical Answers.

Paludan-Müller  AS, Boesen  K, Klerings  I, Jørgensen  KJ, Munkholm  K. Hand cleaning with ash for reducing the spread of viral and bacterial infections: a rapid review. Cochrane Database of Systematic Reviews 2020, Issue 4. Art. No.: CD013597. DOI: 10.1002/14651858.CD013597

New Reviews

Conterno  LO, Turchi  MD, Corrêa  I, Monteiro de Barros Almeida  RA. Anthelmintic drugs for treating ascariasis. Cochrane Database of Systematic Reviews 2020, Issue 4. Art. No.: CD010599. DOI: 10.1002/14651858.CD010599.pub2

A team from Brazil, led by Lucieni O Conterno, has completed this new review, which compares the efficacy and safety of anthelmintic drugs (albendazole, mebendazole, ivermectin) used for treating people with Ascaris infection. Ascaris lumbricoides is a common infection, and mainly affects children living in low‐income areas. The authors included 30 parallel‐group RCTs, which enrolled 6442 participants from 17 countries across Africa, Asia, Central America and the Caribbean, and South America. Single dose of albendazole (four trials), mebendazole (three trials) or ivermectin (one trial) were compared to placebo. Single‐dose of albendazole, mebendazole, and ivermectin all appeared effective against Ascaris lumbricoides infection, yielding high parasitological cure at 14 to 60 days and large reductions in eggs excreted, with no differences detected between them. The drugs appear to be safe to treat children and adults with confirmed Ascaris infection. The authors conclude that albendazole, mebendazole, ivermectin are all effective against ascariasis, and it is unclear whether any outstanding questions regarding their use remain.

 Murray  M, Hine  P. Treating progressive disseminated histoplasmosis in people living with HIV. Cochrane Database of Systematic Reviews 2020, Issue 4. Art. No.: CD013594. DOI: 10.1002/14651858.CD013594 (28 Apr)

New Protocols

Deeks JJ, Dinnes J, Takwoingi Y, Davenport C, Leeflang MMG, Spijker R, Hooft L, Van den Bruel A, Emperador D, Dittrich S.  Diagnosis of SARS‐CoV‐2 infection and COVID‐19: accuracy of signs and symptoms; molecular, antigen, and antibody tests; and routine laboratory markers Cochrane Database of Systematic Reviews 2020, Issue 4. Art. No.: CD013596. DOI: 10.1002/14651858.CD013596.

Singh B, Ryan H, Kredo T, Chaplin M, Fletcher T. Chloroquine or hydroxychloroquine for prevention and treatment of COVID‐19. Cochrane Database of Systematic Reviews 2020, Issue 4. Art. No.: CD013587. DOI: 10.1002/14651858.CD013587

2020 Issue 3

No publications produced for Issue 3

2020 Issue 2 

No publications produced for Issue 2

2020 Issue 1 

No publications produced for Issue 1