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COVID-19 (18)
Accuracy of routine laboratory tests to predict mortality and deterioration to severe or critical COVID-19 in people with SARS-CoV-2 (protocol stage)
Can international travel-related control measures contain the spread of the COVID-19 pandemic?
Diagnosis of SARS-CoV-2 infection and COVID-19: accuracy of signs and symptoms; molecular, antigen, and antibody tests; and routine laboratory markers (protocol stage)
Hand cleaning with ash for reducing the spread of viral and bacterial infections: a rapid review
Quarantine alone or in combination with other public health measures to control COVID-19: a rapid review
Electronic and animal noses for detecting SARS-CoV-2 infection (protocol stage)
Favipiravir for treating COVID-19 (protocol stage)
Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection
Routine laboratory testing to determine if a patient has COVID-19
Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19
Thoracic imaging tests for the diagnosis of COVID-19
Interventions to increase COVID-19 vaccine uptake 
Chloroquine or hydroxychloroquine for prevention and treatment of COVID-19
Ivermectin for preventing and treating COVID-19
Prognostic accuracy of imaging findings for predicting morbidity and mortality in patients with COVID-19 (protocol stage)
Renin-angiotensin system inhibitors for treating COVID-19 in adults (protocol stage)
What is the best way to support resilience and mental well-being in frontline healthcare professionals during and after a pandemic?
Antibody tests for identification of current and past infection with SARS-CoV-2
HIV (18)
Diagnostics (4)
Accuracy of measures for antiretroviral adherence in people living with HIV
Point-of-care viral load tests to detect high HIV viral load in people living with HIV/AIDS attending health facilities
Point-of-care tests detecting HIV nucleic acids for diagnosis of HIV-1 or HIV-2 infection in infants and children aged 18 months or less
Symptom screening for active tuberculosis in pregnant women living with HIV (protocol stage)
Prevention (4)
Isoniazid for preventing tuberculosis in HIV-infected children
Primary antifungal prophylaxis for cryptococcal disease in HIV-positive people
School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents
Vitamin A supplements for reducing mother-to-child HIV transmission
Treatment (8)
Antihelminthics in helminth-endemic areas: effects on HIV disease progression
Antiretroviral resistance testing in HIV-positive people
Psychosocial group interventions to improve psychological well-being in adults living with HIV
Efavirenz or nevirapine in three-drug combination therapy with two nucleoside or nucleotide-reverse transcriptase inhibitors for initial treatment of HIV infection in antiretroviral-naïve individuals
Interleukin-2 as an adjunct to antiretroviral therapy for HIV-positive adults
Micronutrient supplementation in adults with HIV infection
Early versus delayed antiretroviral treatment in HIV-positive people with cryptococcal meningitis
Treatment for HIV-associated cryptococcal meningitis
Delivery strategies (2)
Psychosocial group interventions to improve psychological well-being in adults living with HIV
Rapid initiation of antiretroviral therapy for people living with HIV
Malaria (76)
Diagnostics (5)
Glucose-6-phosphate dehydrogenase deficiency near-patient tests for tafenoquine or primaquine use with Plasmodium vivax malaria (protocol stage)
Rapid diagnostic tests for diagnosing uncomplicated malaria in endemic countries
Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings
Rapid diagnostic tests for malaria in endemic countries
Rapid diagnostic tests for diagnosing uncomplicated non-falciparum or malaria in endemic countries
Prevention (29)
Vaccines (3)
Vaccines for preventing malaria (SPf66)
Vaccines for preventing malaria (blood-stage)
Vaccines for preventing malaria (pre-erythrocytic)
Vector Control (14)
Indoor residual spraying for preventing malaria in communities using insecticide-treated nets
Electronic mosquito repellents for preventing mosquito bites and malaria infection
Larvivorous fish for preventing malaria transmission
House modifications for preventing malaria
Indoor residual spraying for preventing malaria
Insecticide space spraying for preventing malaria transmission
Insecticide-treated nets for preventing malaria
Insecticide-treated nets for preventing malaria in pregnancy
Larviciding to prevent malaria transmission
Mosquito repellents for malaria prevention
Piperonyl butoxide (PBO) combined with pyrethroids in insecticide-treated nets to prevent malaria in Africa
Volatile pyrethroid spatial repellents for malaria prevention (protocol stage)
Topical repellents for malaria prevention
Mosquito aquatic habitat modification and manipulation interventions to control malaria
Drugs for prevention for people living in endemic areas (11)
Primaquine or other 8-aminoquinolines for reducing transmission
Intermittent preventive treatment for malaria in children living in areas with seasonal transmission
Intermittent preventive treatment for malaria in infants
Mass drug administration for malaria
Intermittent preventive antimalarial treatment for children with anaemia
Intermittent preventive treatment regimens for malaria in HIV-positive pregnant women
Malaria chemoprophylaxis in sickle cell disease
Ivermectin treatment in humans for reducing malaria transmission
Mefloquine for preventing malaria in pregnant women
Primaquine alternative dosing schedules for preventing malaria relapse in people with
Drugs for preventing malaria in pregnant women in endemic areas: any drug regimen versus placebo or no treatment
Drugs for prevention for travellers (1)
Mefloquine for preventing malaria during travel to endemic areas
Treatment (39)
Treatment of uncomplicated falciparum malaria (21)
Single agent (5)
Amodiaquine for treating malaria
Azithromycin for treating uncomplicated malaria
Intrarectal quinine versus intravenous or intramuscular quinine for treating malaria
Methylene blue for treating malaria (protocol stage)
Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria
Combined treatment, non-artemisinin based (3)
Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria
Chlorproguanil-dapsone for treating uncomplicated malaria
Atovaquone-proguanil for treating uncomplicated Plasmodium falciparum malaria
Combined treatment, artemisinin based (12)
Mass drug administration for malaria
Artemether-lumefantrine (four-dose regimen) for treating uncomplicated falciparum malaria
Artemether-lumefantrine (six-dose regimen) for treating uncomplicated falciparum malaria
Artemisinin derivatives for treating severe malaria
Artemisinin derivatives for treating uncomplicated malaria
Artemisinin-based combination therapy for treating uncomplicated malaria
Artemisinin-naphthoquine for treating uncomplicated malaria
Artesunate plus mefloquine versus mefloquine for treating uncomplicated malaria
Dihydroartemisinin-piperaquine for treating uncomplicated malaria
Adding rapid diagnostic tests to community-based programmes for treating malaria
Sulfadoxine-pyrimethamine plus artesunate versus sulfadoxine-pyrimethamine plus amodiaquine for treating uncomplicated malaria
Paediatric formulations of artemisinin-based combination therapies for treating uncomplicated malaria in children
Drugs for treatment in special groups (1)
Drugs for treating uncomplicated malaria in pregnant women
Treatment of vivax malaria (3)
Artemisinin-based combination therapy for treating uncomplicated malaria
Primaquine for preventing relapse in people with malaria treated with chloroquine
Tafenoquine for preventing relapse in people with Plasmodium vivax malaria
Treatment of severe malaria (7)
Artemether for severe malaria
Artemisinin derivatives for treating severe malaria
Artesunate versus quinine for treating severe malaria
High first dose quinine regimen for treating severe malaria
Intramuscular arteether for treating severe malaria
Intrarectal quinine versus intravenous or intramuscular quinine for treating malaria
Pre-referral rectal artesunate for severe malaria
Adjunctive treatment of severe malaria (5)
Blood transfusion for treating malarial anaemia
Steroids for treating cerebral malaria
Iron-chelating agents for treating malaria
Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria
Routine anticonvulsants for treating cerebral malaria
Symptomatic treatment (3)
Antipyretic measures for treating fever in malaria
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas (protocol stage)
Oral iron supplements for children in malaria-endemic areas
Delivery strategies (3)
Mass drug administration for malaria
Rapid diagnostic tests versus clinical diagnosis for managing people with fever in malaria endemic settings
Unit-dose packaged drugs for treating malaria
Tuberculosis (50)
Diagnostics (15)
Abdominal ultrasound for diagnosing abdominal tuberculosis or disseminated tuberculosis with abdominal involvement in HIV-positive individuals
Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis
Symptom- and chest-radiography screening for active pulmonary tuberculosis in HIV-negative adults and adults with unknown HIV status
Xpert MTB/RIF and Xpert Ultra assays for screening for pulmonary tuberculosis and rifampicin resistance in adults, irrespective of signs or symptoms
Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults
Impact of diagnostic strategies for tuberculosis using lateral flow urine lipoarabinomannan assay in people living with HIV
Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV
Rapid molecular tests for tuberculosis and tuberculosis drug resistance: a qualitative evidence synthesis of recipient and provider views
Screening tests for active pulmonary tuberculosis in children
Symptom screening for active tuberculosis in pregnant women living with HIV (protocol stage)
GenoType MTBDRassay for resistance to second-line anti-tuberculosis drugs
Truenat MTB assays for pulmonary tuberculosis and rifampicin resistance in adults (protocol stage)
Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin
Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis
Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children
Prevention (6)
Rifamycins (rifampicin, rifabutin and rifapentine) compared to isoniazid for preventing tuberculosis in HIV-negative people at risk of active TB
Isoniazid for preventing tuberculosis in non-HIV infected persons
Isoniazid for preventing tuberculosis in HIV-infected children
MVA85A vaccine to enhance BCG for preventing tuberculosis
Mycobacterium vaccae immunotherapy for treating tuberculosis
Treating BCG-induced disease in children
Treatment (18)
Drugs (15)
Adjunctive steroid therapy for managing pulmonary tuberculosis
Corticosteroids for managing tuberculous meningitis
Fixed-dose combinations of drugs versus single-drug formulations for treating pulmonary tuberculosis
Linezolid for drug-resistant pulmonary tuberculosis
Drugs for preventing tuberculosis in people at risk of multiple-drug-resistant pulmonary tuberculosis
Pharmacological and psychological interventions for depression in people with tuberculosis (protocol stage)
Regimens of less than six months for treating tuberculosis
Rifabutin for treating pulmonary tuberculosis
Shortened treatment regimens versus the standard regimen for drug-sensitive pulmonary tuberculosis
Six-month therapy for abdominal tuberculosis
Fluoroquinolones for treating tuberculosis (presumed drug-sensitive)
Fully intermittent dosing with drugs for treating tuberculosis in adults
Interventions for treating tuberculous pericarditis
Intermittent versus daily therapy for treating tuberculosis in children
Corticosteroids for tuberculous pleurisy
Other (3)
Routine surgery in addition to chemotherapy for treating spinal tuberculosis
Low level laser therapy for treating tuberculosis
Nutritional supplements for people being treated for active tuberculosis
Delivery strategies (11)
Community views on active case finding for tuberculosis in low- and middle-income countries: a qualitative evidence synthesis (protocol stage)
Contact tracing strategies in household and congregate environments to identify cases of tuberculosis in low- and moderate-incidence populations
Patient education and counselling for promoting adherence to treatment for tuberculosis
Digital devices for tuberculosis treatment adherence (protocol stage)
Directly observed therapy for treating tuberculosis
Incentives and enablers to improve adherence in tuberculosis
Interventions to increase tuberculosis case detection at primary healthcare or community-level services
Reminder systems to improve patient adherence to tuberculosis clinic appointments for diagnosis and treatment
Active case finding in contacts of people with tuberculosis
Six months therapy for tuberculous meningitis
Six-month therapy for abdominal tuberculosis
Diarrhoeal infections (30)
Principles of prevention and management (20)
Prevention (7)
Hand-washing promotion for preventing diarrhoea
Fly control to prevent diarrhoea in children
Interventions to improve disposal of child faeces for preventing diarrhoea and soil-transmitted helminth infection
Interventions to improve disposal of human excreta for preventing diarrhoea
Interventions to improve sanitation for preventing diarrhoea
Interventions to improve water quality for preventing diarrhoea
Interventions to improve water, sanitation, and hygiene for preventing soil-transmitted helminth infection
Rehydration (4)
Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children
Oral versus intravenous rehydration for treating dehydration due to gastroenteritis in children
Polymer-based oral rehydration solution for treating acute watery diarrhoea
Reduced osmolarity oral rehydration solution for treating dehydration caused by acute diarrhoea in children
Anti-infective treatment (4)
Antiamoebic drugs for treating amoebic colitis
Antibiotic treatment for travellers' diarrhoea
Probiotics for treating acute infectious diarrhoea
Probiotics for treating persistent diarrhoea in children
Management (5)
Oral zinc for treating diarrhoea in children
Racecadotril for acute diarrhoea in children
Early versus Delayed Refeeding for Children with Acute Diarrhoea
Smectite for acute infectious diarrhoea in children
Lactose avoidance for young children with acute diarrhoea
Prevention and management of specific infections (10)
Cholera (5)
Antimicrobial drugs for treating cholera
Vaccines for preventing cholera: killed whole cell or other subunit vaccines (injected)
Oral rehydration salt solution for treating cholera: ≤ 270 mOsm/L solutions vs ≥ 310 mOsm/L solutions
Oral vaccines for preventing cholera
Vaccines for preventing enterotoxigenic (ETEC) diarrhoea
Giardiasis (1)
Drugs for treating giardiasis
Rotavirus (2)
Vaccines for preventing rotavirus diarrhoea: vaccines in use
Rotavirus vaccine for preventing diarrhoea
Salmonellosis (1)
Antimicrobials for treating symptomatic non-typhoidal infection
Shigellosis (1)
Antibiotic therapy for Shigella dysentery
Neglected tropical diseases (19)
Buruli ulcer (1)
Drugs for treating Buruli ulcer ( disease)
Human African Trypanosomiasis (2)
Chemotherapy for second-stage Human African trypanosomiasis
Chemotherapy for second-stage human African trypanosomiasis: drugs in use
Lymphatic filariasis (3)
Albendazole alone or in combination with microfilaricidal drugs for lymphatic filariasis
Community views on mass drug administration for filariasis: a qualitative evidence synthesis
Diethylcarbamazine (DEC)-medicated salt for community-based control of lymphatic filariasis
Mycetoma (1)
Drug therapy for Mycetoma (protocol stage)
Schistosomiasis (4)
Biannual praziquantel treatment for schistosomiasis (protocol stage)
Drugs for treating infection
Drugs for treating urinary schistosomiasis
Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas
Visceral leishmaniasis (3)
Nutritional supplements for patients being treated for active visceral leishmaniasis
Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease
Vector and reservoir control for preventing leishmaniasis
Cysticercosis (1)
Anthelmintics for people with neurocysticercosis
Dengue (3)
Diagnosis (0)
Prevention (2)
Control methods for and (protocol stage)
Wolbachia-carrying Aedes mosquitoes for preventing dengue infection (protocol stage)
Treatment (1)
Corticosteroids for dengue infection
Helminths, soil transmitted (1)
Public health deworming programmes for soil-transmitted helminths in children living in endemic areas
Other (32)
Angiostrongylus (0)
Anthrax (1)
Vaccines for preventing anthrax
Antimicrobial resistance (1)
Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection
Ascariasis (1)
Anthelmintic drugs for treating ascariasis
Brucellosis (1)
Antibiotics for treating human brucellosis
Crimean Congo haemorrhagic fever (1)
Ribavirin for treating Crimean Congo haemorrhagic fever
Epidemic typhus (0)
Fever management (3)
Combined and alternating paracetamol and ibuprofen therapy for febrile children
Paracetamol versus placebo or physical methods for treating fever in children
Physical methods versus drug placebo or no treatment for managing fever in children
Food supplements for preventing infections (1)
Vitamin D supplementation for preventing infections in children under five years of age
Gnathostomiasis (0)
Headlice (1)
Interventions for treating head lice: a network meta-analysis (protocol stage)
Histoplasmosis (1)
Treating progressive disseminated histoplasmosis in people living with HIV
Biomarkers for vitamin deficiency (1)
Selected laboratory-based biomarkers for assessing vitamin A deficiency in at-risk individuals (protocol stage)
Japanese encephalitis (1)
Vaccines for preventing Japanese encephalitis
Melioidosis (1)
Interventions for treating melioidosis
Paracoccidioidomycosis (1)
Drugs for treating paracoccidioidomycosis
Paraveterinary services impact on human health (1)
Community animal health services for improving household wealth and health status of low income farmers
Plague (2)
Rapid diagnostic tests for plague
Vaccines for preventing plague
Scabies (2)
Interventions for treating scabies
Ivermectin and permethrin for treating scabies
Scrub typhus (1)
Antibiotics for treating scrub typhus
Smallpox (1)
Vaccines for preventing smallpox
Snake bites (1)
Interventions for preventing reactions to snake antivenom
Strongyloidiasis (1)
Ivermectin versus albendazole or thiabendazole for infection
Tick-borne encephalitis (1)
Vaccines for preventing tick-borne encephalitis
Trichomoniasis (1)
Interventions for treating trichomoniasis in women
Typhoid and paratyphoid fever (enteric fever) (5)
Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins
Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever)
Rapid diagnostic tests for typhoid and paratyphoid (enteric) fever
Typhoid conjugate vaccines for preventing typhoid fever (enteric fever) (protocol stage)
Vaccines for preventing typhoid fever
Zika (1)
Laboratory tests for diagnosis of congenital Zika virus in fetuses and neonates (protocol stage)

Related content

The protocol for our review “Deworming drugs for soil-transmitted intestinal worms in children: effects on nutritional indicators, haemoglobin, and school performance” was first published in 1997, prior to creation of the online Cochrane Library. A copy of this document can be found here.